Product photo

Product details

Name: Phytosphingosine, Kinase Activator

Size: 5 mg

Catalog no.: SIH-524-5MG

Order on Gentaur.com

Total weight (kg)

0.25

Net weight (g)

0.005

Country of production

Canada

Storage recommendations

-20ÂșC

PubChem number

122121

CAS number

554-62-1

Stock availabilitIn Stock

In Stock

Product type

Activator

Chemical formula

C18H39NO3

Release date

1-Oct-2014

Molecular weight

317.5 g/mol

Tested reactivity

To be tested

Physical appearance

White powder

Tested applications

To be tested

Warning information

Non-hazardous

PubMed number

Refer to PubMed

Product category

Small Molecules

Shipping recommendations

Shipped Ambient

Description

Kinase Activator

Primary research fields

Cancer, Oxidative Stress

Purity pourcentage

>98% (TLC); NMR (Conforms)

Soluble in

Soluble to 2 mg/ml in ethanol

Other name

(2S,3R,4R)-Octadecane-1,2,3,4-tetraol

Origin

Isolated from Saccharomyces cerevisiae

Bibliography

1. Fischer C., et al. (2013) Skin Pharmacol Physiol. 26(1): 36-44.

Safety information

Classification: Not WHMIS controlled. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

Representative figure legend

Chemical structure of Phytosphingosine (SIH-524), a Antibacterial. CAS #: 554-62-1. Molecular Formula: C18H39NO3. Molecular Weight: 317.5 g/mol. Chemical structure of Phytosphingosine, a Antibacterial (SIH-524). CAS # 554-62-1. Molecular Formula: C18H39NO3.

Scientific context

Phytosphingosine is a naturally occurring component found in yeast, plants and animals. In yeast, it is involved in mediating the heat stress response. Phytosphingosine has been found to be pro-apoptotic in certain cancer cell lines. It is thought to activate the p38 MAPK pathway, followed by release of cytochrome c and activation of caspase 3, ultimately leading to programed cell death.

Menu