Product photo
Product details
Name: Phytosphingosine for cell activation
Size: 250 mg
Catalog no.: 2426-250
Order on Gentaur.comIs this a salt?
No
Is it cell-permeable?
Yes
Peptide sequence
N/A
Supplied with
N/A
Tissue
cell
Molecular weight
317.51
Storage condition
-20 ̊C
Shipping condition
gel pack
CAS number
554-62-1
Maximum time for storage
36 months
Physical appearance
White solid
Category
Biochemicals
Purification
≥98% by TLC
Reconstitute instructions
EtOH (~ 2 mg/ml)
Molecular formula
C₁₈H₃₉NO₃
Storage instructions
Protect from air and moisture
Additional description
For cells, cell lines and tissues in culture till half confluency.
Other name
4-Hydroxysphinganine, D-Ribo-1,3,4-trihydroxy-2-aminooctadecane, D-Ribo-2-aminooctadecane-1,3,4-triol, PHS
Description
Phytosphingosine is a phospholipid structurally similar to Sphingosine (Cat. No. 2425). The physiological roles of phytosphingosine are largely unknown. Phytosphingosine induces apoptosis in human T-cell lymphoma and non-small cell lung cancer cells, and induces caspase-independent cytochrome c release from mitochondria. In the presence of caspase inhibitors, phytosphingosine-induced apoptosis is almost completely suppressed, suggesting that phytosphingosine-induced apoptosis is largely dependent on caspase activities.