Product photo

Product details

Name: Phytosphingosine for cell activation

Size: 50 mg

Catalog no.: 2426-50

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Is this a salt?

No

Is it cell-permeable?

Yes

Peptide sequence

N/A

Supplied with

N/A

Tissue

cell

Molecular weight

317.51

Storage condition

-20 ̊C

Shipping condition

gel pack

CAS number

554-62-1

Maximum time for storage

36 months

Physical appearance

White solid

Category

Biochemicals

Purification

≥98% by TLC

Reconstitute instructions

EtOH (~ 2 mg/ml)

Molecular formula

C₁₈H₃₉NO₃

Storage instructions

Protect from air and moisture

Additional description

For cells, cell lines and tissues in culture till half confluency.

Other name

4-Hydroxysphinganine, D-Ribo-1,3,4-trihydroxy-2-aminooctadecane, D-Ribo-2-aminooctadecane-1,3,4-triol, PHS

Description

Phytosphingosine is a phospholipid structurally similar to Sphingosine (Cat. No. 2425). The physiological roles of phytosphingosine are largely unknown. Phytosphingosine induces apoptosis in human T-cell lymphoma and non-small cell lung cancer cells, and induces caspase-independent cytochrome c release from mitochondria. In the presence of caspase inhibitors, phytosphingosine-induced apoptosis is almost completely suppressed, suggesting that phytosphingosine-induced apoptosis is largely dependent on caspase activities.

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