Product photo
Product details
Name: Phytosphingosine, Kinase Activator
Size: 25 mg
Catalog no.: SIH-524-25MG
Order on Gentaur.comTotal weight (kg)
0.25
Net weight (g)
0.025
Country of production
Canada
Storage recommendations
-20ºC
PubChem number
122121
CAS number
554-62-1
Stock availabilitIn Stock
In Stock
Product type
Activator
Chemical formula
C18H39NO3
Release date
1-Oct-2014
Molecular weight
317.5 g/mol
Tested reactivity
To be tested
Physical appearance
White powder
Tested applications
To be tested
Warning information
Non-hazardous
PubMed number
Refer to PubMed
Product category
Small Molecules
Shipping recommendations
Shipped Ambient
Description
Kinase Activator
Primary research fields
Cancer, Oxidative Stress
Purity pourcentage
>98% (TLC); NMR (Conforms)
Soluble in
Soluble to 2 mg/ml in ethanol
Other name
(2S,3R,4R)-Octadecane-1,2,3,4-tetraol
Origin
Isolated from Saccharomyces cerevisiae
Bibliography
1. Fischer C., et al. (2013) Skin Pharmacol Physiol. 26(1): 36-44.
Safety information
Classification: Not WHMIS controlled. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Representative figure legend
Chemical structure of Phytosphingosine (SIH-524), a Antibacterial. CAS #: 554-62-1. Molecular Formula: C18H39NO3. Molecular Weight: 317.5 g/mol. Chemical structure of Phytosphingosine, a Antibacterial (SIH-524). CAS # 554-62-1. Molecular Formula: C18H39NO3.
Scientific context
Phytosphingosine is a naturally occurring component found in yeast, plants and animals. In yeast, it is involved in mediating the heat stress response. Phytosphingosine has been found to be pro-apoptotic in certain cancer cell lines. It is thought to activate the p38 MAPK pathway, followed by release of cytochrome c and activation of caspase 3, ultimately leading to programed cell death.